Download Complete Ammeliorative Properties Of Methanol Leaf Extract Of Mucuna Pruriens On The Kidney Markers Of Malaria Infected Mice Research Materials (PDF/DOC)
The research on Mucuna pruriens was to know its ameliorative efficacy on the kidney markers of malaria infected mice. The antimalaria effect was evaluated against Plasmodium berghei stain of 25 mice.The twenty five (25) adult albino mice of both sexes which weighed 20g-36g were grouped into five(1-5) of five mice per group which was used to carry out the experiment. Group 1 which served as negative control received 10ml/kg of 5% tween 80,group 2, which is positive or standard control received 0.95mg/kg of standard drug (ACT), groups 3, 4 and 5 received 100mg/kg, 200mg/kg and 400mg/kg body weight of the extract of Mucuna pruriens respectively. Malaria was induced using Plasmodium berghei in which the malaria infected mice were examined for parasitemia on day 4 and 8 of the treatment.
The creatinine, bilirubin and serum urea levels were determined using Randox and Teco kits .The curative percentage of the animals in groups (1-5) were recorded. In day 4, The curative percentage were 0%, 41.43%, 39.34%, 46.1% and 67.93% respectively and day 8 values are as follows 28.13%, 97.19%, 87.70%, 80% and 95.19%. The values for kidney markers in days 4 for Urea were (44.00 9.79, 36 40 , 35 and 46.67 , creatinine values (0.62 2.62 4.46 3.13 2.53 ) and bilirubin values (21.9 1.41, 21.4 and 22.43 while the values in day 8 for Urea were (40.00 and 45.00 and creatinine values were (24.26 and 23.93 while that of bilirubin were (24.26 and 23.93 for groups (1-5) respectively. The research showed that the extract can cure malaria without affecting the kidney markers and can be added in formulating antimalaria drugs.
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The abstract section provides a concise summary of the Ammeliorative Properties Of Methanol Leaf Extract Of Mucuna Pruriens On The Kidney Markers Of Malaria Infected Mice, including the issue statement, methodology, findings, and conclusion
The introduction section introduces the Ammeliorative Properties Of Methanol Leaf Extract Of Mucuna Pruriens On The Kidney Markers Of Malaria Infected Mice by offering background information, stating the problem, aims, research questions or hypotheses, and the significance of the research
The literature review section presents a review of related literature that supports the current research on the Ammeliorative Properties Of Methanol Leaf Extract Of Mucuna Pruriens On The Kidney Markers Of Malaria Infected Mice, systematically identifying documents with relevant analyzed information to help the researcher understand existing knowledge, identify gaps, and outline research strategies, procedures, instruments, and their outcomes
The conclusion section of the Ammeliorative Properties Of Methanol Leaf Extract Of Mucuna Pruriens On The Kidney Markers Of Malaria Infected Mice summarizes the key findings, examines their significance, and may make recommendations or identify areas for future research
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