Clinico-Pathological Effects Of Experimental Ascaris Suum Infection In Yankasa Lambs
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Clinico-Pathological Effects Of Experimental Ascaris Suum Infection In Yankasa Lambs
Ascaris suum is a parasitic nematode (roundworm) that primarily infects pigs. In experimental studies, researchers may infect animals with Ascaris suum to study the effects of the infection. Keep in mind that the findings can vary based on the specific conditions of the experiment, such as the dosage of infective larvae, duration of infection, and the overall health of the animals.
Here are some general clinico-pathological effects that might be observed in animals infected with Ascaris suum:
- Clinical Signs:
- Weight loss
- Poor growth
- Reduced feed efficiency
- Lethargy
- Respiratory distress (due to migration of larvae)
- Pathological Effects:
- Damage to the intestinal mucosa: Ascaris suum adult worms reside in the small intestine, and their feeding can cause damage to the mucosal lining.
- Obstruction of the intestinal lumen: In severe cases, a large number of worms may lead to intestinal blockages.
- Migration of larvae: Larvae migration through various organs and tissues can cause pathological changes, particularly in the liver and lungs.
- Immune Response:
- Inflammatory response: The host’s immune system may react to the presence of Ascaris suum, leading to inflammation in affected tissues.
- Immunopathology: In some cases, the immune response can contribute to tissue damage.
- Blood and Hematological Changes:
- Eosinophilia: Elevated levels of eosinophils in the blood are common in response to parasitic infections.
- Anemia: Chronic infections may lead to anemia.
- Respiratory Distress:
- Larval migration through the lungs can lead to coughing and respiratory distress.
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