Download Complete Effect Of Ethanol Extract Of Dennettiatripetala On Liver And Kidney Antioxidant Enzyme Activity And Malondialdehyde Concentration Of Albino Wistar Rats Exposed To CCl4 Research Materials (PDF/DOC)
The effect of ethanol extract of Dennettiatripetala on rats exposed to carbon tetrachloride was investigated. Ethanol extract of the plant was prepared using standard procedure. Sets of 30 female wistar albino rats were divided into 6 groups containing five animals each and were treated orally with increasing doses of ethanol extract of Dennettiatripetala for two weeks. CCl4 was diluted with olive oil in a 1:1 ratio and administered once by oral route at the end of the extract administration. Results from the study showed non- significant decreases in the levels of catalase and SOD activities (P>0.05) in the CCl4 group compared to the control. The extract treatment however produced a higher activity for the antioxidant enzymes compared to the CCl4treated groups. The results also showed increased levels of MDA concentration (P<0.05) in the CCl4 group whereas extract treated rats showed lower concentrations of MDA. The overall results suggests that the ethanolic extract of Dennettiatripetala may have moderate hepatoprotective effect in the CCl4 induced rats.
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The abstract section provides a concise summary of the Effect Of Ethanol Extract Of Dennettiatripetala On Liver And Kidney Antioxidant Enzyme Activity And Malondialdehyde Concentration Of Albino Wistar Rats Exposed To CCl4, including the issue statement, methodology, findings, and conclusion
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