Antimicrobial Activity And Phytochemical Analysis Of Aqueous And Methanoic Extract Of Celosia Argentea

Celosia argentea is used traditionally for the treatment of wounds, dysentary, fatique, menstral bleeding, osteoporosis, Atheros-clerosis etc. This investigation was aimed to analyze the phytochemical (phyto constituents) that is present in the aqueous and methanoic extracts of celosia argentea leaf and also the antimicrobial activity of celosia argentea leaf extracts. It was done to extract the bioactive compounds from this medicinal plant which permits the demonstration of their physiological activity. The powdered leaf was subjected to extractions using a polar solvent which was distilled water (100ml) and 100ml of methanol using soxhlet extractor. The anti-microbial activity was also carried out by inoculating different micro-organisms like staphylococcus aureus, Escherichia Coli, Streptococcus spp, Pseudomonas aeroginosa, candida albicans and Aspergillusniger into different nutrient agar dish by streaking method. The extracts were then introduced into the bored well in the solidified agar dish and were incubated at 121⁰C for 24hrs. The preliminary phytochemical analysis revealed that the leaf extract of celosia argentea contain phenols ,saponins, anthranoids, anthraquinone, alkaloids, tannins and phylobatannins. The microbial activity revealed that the minimum inhibitory concentration (MIC) as well as the minimum bactericidal concentration (MBC) ranged from 125mg/ml to 250mg/ml.

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