Pathology Final Year Project Topics & Materials PDF

List of Best Pathology Project Topics & their Complete (PDF, DOC) Materials for Students

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Recent Pathology Project Topics & Research Material Areas for Final Year & Undergraduate Students (in Nigeria & Other Countries)

  • Cancer Pathogenesis: Investigate the molecular mechanisms underlying the initiation, progression, and metastasis of various types of cancer, including breast, lung, colorectal, and prostate cancer. Explore the role of genetic mutations, epigenetic modifications, and signaling pathways in driving oncogenesis.
  • Infectious Disease Pathology: Focus on understanding the pathology of infectious diseases caused by bacteria, viruses, fungi, and parasites. Research areas may include the host-pathogen interactions, immune responses, and mechanisms of pathogen-induced tissue damage.
  • Neuropathology: Study the pathological basis of neurological disorders such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and stroke. Investigate the molecular and cellular mechanisms underlying neurodegeneration and neuronal injury.
  • Cardiovascular Pathology: Explore the pathology of cardiovascular diseases such as atherosclerosis, myocardial infarction, heart failure, and hypertension. Investigate the role of inflammation, oxidative stress, and vascular remodeling in cardiovascular pathology.
  • Renal Pathology: Investigate the pathology of renal diseases including glomerulonephritis, tubulointerstitial nephritis, diabetic nephropathy, and polycystic kidney disease. Study the mechanisms of kidney injury, fibrosis, and dysfunction.
  • Hematopathology: Focus on the pathology of hematological disorders such as leukemia, lymphoma, and myeloproliferative neoplasms. Investigate the molecular and cellular basis of abnormal hematopoiesis and hematological malignancies.
  • Gastrointestinal Pathology: Study the pathology of gastrointestinal disorders including inflammatory bowel disease, celiac disease, gastritis, and gastrointestinal cancers. Investigate the role of microbiota, immune dysregulation, and environmental factors in gastrointestinal pathology.
  • Respiratory Pathology: Investigate the pathology of respiratory diseases such as chronic obstructive pulmonary disease (COPD), asthma, pulmonary fibrosis, and lung cancer. Explore the mechanisms of airway inflammation, remodeling, and lung injury.
  • Musculoskeletal Pathology: Focus on the pathology of musculoskeletal disorders including osteoarthritis, rheumatoid arthritis, osteoporosis, and musculoskeletal tumors. Investigate the mechanisms of joint degeneration, bone remodeling, and cartilage degradation.
  • Endocrine Pathology: Study the pathology of endocrine disorders such as diabetes mellitus, thyroid disorders, adrenal disorders, and pituitary disorders. Investigate the hormonal imbalances, metabolic dysregulation, and organ dysfunction associated with endocrine pathology.
  • Dermatopathology: Investigate the pathology of skin diseases including psoriasis, eczema, dermatitis, and skin cancer. Study the mechanisms of skin inflammation, hyperproliferation, and tissue remodeling.
  • Genetic Disorders: Explore the pathology of genetic diseases such as cystic fibrosis, sickle cell disease, Huntington’s disease, and muscular dystrophy. Investigate the molecular basis of genetic mutations, protein misfolding, and cellular dysfunction.
  • Immunopathology: Study the pathology of immune-mediated diseases such as autoimmune diseases, immunodeficiency disorders, and hypersensitivity reactions. Investigate the mechanisms of immune dysregulation, tissue inflammation, and autoantibody production.
  • Developmental Pathology: Investigate the pathology of developmental disorders such as congenital anomalies, developmental delays, and genetic syndromes. Study the molecular and cellular mechanisms underlying abnormal development and organogenesis.
  • Environmental Pathology: Focus on the pathology of diseases caused by environmental factors such as pollution, toxins, radiation, and occupational exposures. Investigate the mechanisms of environmental toxicity, tissue damage, and disease pathogenesis.
  • Reproductive Pathology: Study the pathology of reproductive disorders including infertility, endometriosis, polycystic ovary syndrome (PCOS), and reproductive cancers. Investigate the hormonal imbalances, tissue abnormalities, and genetic factors contributing to reproductive pathology.
  • Hepatobiliary Pathology: Investigate the pathology of liver and biliary diseases such as hepatitis, cirrhosis, cholangiocarcinoma, and liver failure. Study the mechanisms of liver injury, fibrosis, and regeneration.
  • Ophthalmic Pathology: Focus on the pathology of eye diseases including age-related macular degeneration, glaucoma, diabetic retinopathy, and cataracts. Investigate the mechanisms of retinal degeneration, optic nerve damage, and visual impairment.
  • Oral Pathology: Study the pathology of oral diseases including periodontal disease, oral cancer, dental caries, and oral mucosal disorders. Investigate the role of microbial pathogens, inflammation, and immune responses in oral pathology.
  • Lymphatic System Pathology: Investigate the pathology of lymphatic disorders such as lymphedema, lymphadenopathy, and lymphatic malformations. Study the mechanisms of lymphatic vessel dysfunction, lymph node pathology, and lymphatic system-related diseases.
  • Bone and Joint Pathology: Focus on the pathology of bone and joint diseases including osteoporosis, osteoarthritis, rheumatoid arthritis, and bone tumors. Investigate the mechanisms of bone resorption, cartilage degradation, and joint inflammation.
  • Thyroid Pathology: Study the pathology of thyroid disorders including hypothyroidism, hyperthyroidism, thyroid nodules, and thyroid cancer. Investigate the hormonal imbalances, autoimmune mechanisms, and genetic factors involved in thyroid pathology.
  • Pancreatic Pathology: Investigate the pathology of pancreatic diseases such as pancreatitis, pancreatic cancer, and pancreatic endocrine tumors. Study the mechanisms of pancreatic inflammation, fibrosis, and tumorigenesis.
  • Stem Cell Pathology: Focus on the pathology of stem cell disorders including bone marrow failure syndromes, stem cell transplantation complications, and stem cell-related cancers. Investigate the molecular and cellular mechanisms underlying abnormal stem cell function and differentiation.
  • Metabolic Disorders: Study the pathology of metabolic diseases such as obesity, metabolic syndrome, diabetes mellitus, and lipid disorders. Investigate the molecular basis of metabolic dysregulation, insulin resistance, and adipose tissue dysfunction.
  • Psychiatric Pathology: Investigate the pathology of psychiatric disorders including depression, schizophrenia, bipolar disorder, and anxiety disorders. Study the neurobiological mechanisms underlying psychiatric symptoms and behavioral abnormalities.
  • Autoimmune Diseases: Focus on the pathology of autoimmune disorders such as rheumatoid arthritis, systemic lupus erythematosus (SLE), multiple sclerosis, and type 1 diabetes. Investigate the mechanisms of autoimmunity, tissue inflammation, and organ damage.
  • Transplant Pathology: Study the pathology of transplant rejection, graft-versus-host disease (GVHD), and transplant-associated complications. Investigate the immunological mechanisms underlying graft rejection, tissue injury, and transplant failure.
  • Vascular Pathology: Investigate the pathology of vascular diseases such as vasculitis, thrombosis, aneurysms, and peripheral artery disease. Study the mechanisms of endothelial dysfunction, vascular inflammation, and vascular remodeling.
  • Pediatric Pathology: Focus on the pathology of pediatric diseases including congenital anomalies, genetic disorders, childhood cancers, and developmental disorders. Investigate the molecular and cellular mechanisms underlying pediatric pathology.
  • Aging-related Pathology: Investigate the pathology of aging-related diseases such as Alzheimer’s disease, cardiovascular diseases, osteoporosis, and age-related macular degeneration. Study the cellular senescence, oxidative stress, and inflammation associated with aging-related pathology.
  • Molecular Pathology: Focus on the molecular mechanisms underlying disease pathogenesis, including genetic mutations, epigenetic modifications, and aberrant signaling pathways. Investigate the molecular biomarkers and therapeutic targets for various diseases.
  • Pharmacological Pathology: Study the pathology of drug-induced toxicities, adverse drug reactions, and drug-drug interactions. Investigate the mechanisms of drug toxicity, cellular damage, and organ dysfunction associated with pharmacological agents.
  • Nutritional Pathology: Investigate the pathology of nutritional deficiencies, metabolic disorders, and diet-related diseases. Study the mechanisms of nutrient metabolism, nutrient absorption, and nutrient-related tissue damage.
  • Stem Cell Therapy and Regenerative Medicine: Explore the pathology of stem cell-based therapies, tissue engineering approaches, and regenerative medicine strategies. Investigate the mechanisms of stem cell engraftment, tissue repair, and functional recovery.
  • Precision Medicine and Personalized Pathology: Investigate the pathology of individualized disease susceptibility, treatment response, and prognosis prediction. Study the molecular biomarkers, genetic profiles, and omics data for personalized medicine approaches.
  • Nanomedicine and Nanopathology: Focus on the pathology of nanomaterials, nanomedicines, and nanotechnology-based therapies. Investigate the mechanisms of nanoparticle interactions, cellular uptake, and nanomaterial-induced tissue responses.
  • Digital Pathology and Artificial Intelligence: Explore the pathology of digital imaging, machine learning algorithms, and artificial intelligence applications. Investigate the use of digital pathology tools for disease diagnosis, prognosis prediction, and therapeutic decision-making.
  • Environmental Toxicology and Pathology: Study the pathology of environmental pollutants, chemical exposures, and toxic substances. Investigate the mechanisms of environmental toxicity, organ damage, and disease development.
  • Regulatory Pathology and Drug Safety: Investigate the pathology of drug development, preclinical safety assessments, and regulatory guidelines. Study the mechanisms of drug-induced toxicities, off-target effects, and safety pharmacology concerns.

Top Final Year Project Project Topics for Pathology Students & Researchers

  1. The Role of Genetic Mutations in Cancer Pathogenesis
  2. Immunohistochemical Markers for Early Diagnosis of Alzheimer’s Disease
  3. Molecular Mechanisms of Autoimmune Diseases
  4. Pathological Changes in the Liver Associated with Chronic Alcoholism
  5. Diagnostic Challenges in Pediatric Pathology
  6. The Impact of Microbiome Dysbiosis on Gastrointestinal Pathology
  7. Emerging Biomarkers for Prognosis in Breast Cancer
  8. Histopathological Characterization of Lung Diseases in Smokers
  9. Pathophysiology of Sepsis-induced Organ Failure
  10. Molecular Basis of Drug Resistance in Infectious Diseases
  11. The Role of Inflammation in Cardiovascular Pathology
  12. Clinicopathological Correlation in Renal Pathology
  13. Epigenetic Modifications in Cancer Progression
  14. Pathological Changes in Neurodegenerative Diseases
  15. Diagnostic Challenges in Soft Tissue Pathology
  16. Immunopathogenesis of Rheumatoid Arthritis
  17. Biomarkers for Early Detection of Ovarian Cancer
  18. Pathological Features of Viral Hepatitis
  19. The Impact of Environmental Factors on Skin Pathology
  20. Molecular Basis of Hematologic Disorders
  21. Immunohistochemical Profiling in Prostate Cancer
  22. Pathological Aspects of Diabetes Mellitus Complications
  23. Genetic Variants in Inherited Cardiac Disorders
  24. Pathology of Endocrine Gland Disorders
  25. Histopathological Changes in Inflammatory Bowel Disease
  26. Molecular Markers for Predicting Response to Cancer Immunotherapy
  27. Pathogenesis of Human Papillomavirus (HPV) Infections
  28. Neuropathology of Traumatic Brain Injury
  29. Pathological Features of Autoimmune Thyroid Disorders
  30. Role of Tumor Microenvironment in Cancer Progression
  31. Pathophysiology of Pulmonary Fibrosis
  32. Molecular Mechanisms of Chemoresistance in Cancer
  33. Diagnostic Challenges in Bone and Joint Pathology
  34. Pathological Changes in Chronic Kidney Disease
  35. Immunohistochemical Profiling in Pancreatic Cancer
  36. Molecular Pathology of Hereditary Cancer Syndromes
  37. Pathogenesis of Inflammatory Neuropathies
  38. Role of Tumor-Infiltrating Lymphocytes in Cancer Prognosis
  39. Diagnostic Approaches in Neuropathology
  40. Histopathological Features of Autoimmune Liver Diseases
  41. Molecular Basis of Muscular Dystrophies
  42. Immunohistochemistry in the Diagnosis of Lymphomas
  43. Pathophysiology of Cystic Fibrosis
  44. Genetic Basis of Congenital Heart Diseases
  45. Pathological Features of Infectious Arthritis
  46. Molecular Markers for Predicting Response to Targeted Therapies
  47. Role of MicroRNAs in Cancer Pathogenesis
  48. Pathological Changes in Gynecologic Cancers
  49. Immunopathogenesis of Psoriasis
  50. Diagnostic Challenges in Hematopathology
  51. Pathological Features of Autoimmune Encephalitis
  52. Molecular Basis of Chronic Obstructive Pulmonary Disease (COPD)
  53. Immunohistochemical Profiling in Renal Cell Carcinoma
  54. Pathophysiology of Acute Respiratory Distress Syndrome (ARDS)
  55. Genetic Susceptibility in Infectious Diseases
  56. Pathological Changes in Autoimmune Hemolytic Anemia
  57. Molecular Mechanisms of Angiogenesis in Cancer
  58. Histopathological Characterization of Skin Tumors
  59. Diagnostic Challenges in Pediatric Neuropathology
  60. Immunopathogenesis of Systemic Lupus Erythematosus
  61. Role of Inflammatory Cytokines in Neurological Disorders
  62. Pathological Features of Gastrointestinal Stromal Tumors (GIST)
  63. Biomarkers for Early Detection of Colorectal Cancer
  64. Pathophysiology of Atherosclerosis
  65. Molecular Basis of Neurofibromatosis
  66. Immunohistochemical Profiling in Head and Neck Cancers
  67. Pathological Changes in Pancreatitis
  68. Genetic Variants in Inflammatory Bowel Disease
  69. Pathogenesis of Idiopathic Pulmonary Fibrosis
  70. Diagnostic Challenges in Dermatopathology
  71. Molecular Markers for Predicting Response to Radiation Therapy
  72. Pathological Features of Cardiomyopathies
  73. Immunopathogenesis of Multiple Sclerosis
  74. Role of Epigenetics in Cardiovascular Diseases
  75. Pathophysiology of Neonatal Respiratory Distress Syndrome
  76. Molecular Basis of Thrombophilia
  77. Immunohistochemical Profiling in Thyroid Cancer
  78. Pathological Changes in Myocardial Infarction
  79. Diagnostic Challenges in Pediatric Cardiac Pathology
  80. Genetic Basis of Neurodegenerative Disorders
  81. Pathological Features of Preeclampsia
  82. Molecular Mechanisms of Drug-Induced Liver Injury
  83. Immunopathogenesis of Inflammatory Lung Diseases
  84. Role of Microenvironment in Tumor Invasion and Metastasis
  85. Pathogenesis of Hemorrhagic Fever Viruses
  86. Pathological Changes in Neurocysticercosis
  87. Molecular Markers for Predicting Response to Chemotherapy
  88. Histopathological Characterization of Bone Marrow Disorders
  89. Diagnostic Challenges in Urological Pathology
  90. Pathological Features of Vascular Malformations
  91. Immunohistochemical Profiling in Sarcomas
  92. Pathophysiology of Autoimmune Hepatitis
  93. Genetic Variants in Alzheimer’s Disease
  94. Pathological Changes in Osteoarthritis
  95. Molecular Basis of Pediatric Cancers
  96. Immunopathogenesis of Chronic Rhinosinusitis
  97. Role of Tumor Microenvironment in Immune Evasion
  98. Pathogenesis of Ischemic Stroke
  99. Diagnostic Challenges in Pediatric Nephropathology
  100. Pathological Features of Autoimmune Pancreatitis
  101. Molecular Mechanisms of Chemokine Signaling in Cancer
  102. Immunohistochemical Profiling in Ovarian Tumors
  103. Pathophysiology of Neonatal Jaundice
  104. Genetic Basis of Autoimmune Skin Disorders
  105. Pathological Changes in Graft-versus-Host Disease
  106. Molecular Markers for Predicting Response to Hormone Therapy
  107. Histopathological Characterization of Soft Tissue Sarcomas
  108. Diagnostic Challenges in Neuromuscular Pathology
  109. Pathological Features of Eosinophilic Esophagitis
  110. Immunopathogenesis of Type 1 Diabetes
  111. Role of Tumor Microenvironment in Immune Therapy Resistance
  112. Pathogenesis of Viral Myocarditis
  113. Pathological Changes in Ovarian Endometriosis
  114. Molecular Basis of Thymic Tumors
  115. Immunohistochemical Profiling in Bladder Cancer
  116. Pathophysiology of Pulmonary Hypertension
  117. Genetic Variants in Parkinson’s Disease
  118. Pathological Features of Fungal Infections in Immunocompromised Patients
  119. Diagnostic Challenges in Pediatric Pulmonary Pathology
  120. Molecular Mechanisms of Antibiotic Resistance in Bacteria
  121. Immunopathogenesis of Allergic Rhinitis
  122. Role of MicroRNAs in Cardiovascular Diseases
  123. Pathogenesis of Viral Hepatitis in Pregnancy
  124. Pathological Changes in Autoimmune Adrenal Disorders
  125. Molecular Markers for Predicting Response to Immunotherapy
  126. Histopathological Characterization of Gliomas
  127. Diagnostic Challenges in Pediatric Gastrointestinal Pathology
  128. Pathological Features of Autoimmune Uveitis
  129. Immunohistochemical Profiling in Renal Transplant Rejection
  130. Pathophysiology of Systemic Sclerosis
  131. Genetic Basis of Polycystic Kidney Disease
  132. Pathological Changes in Neurodevelopmental Disorders
  133. Molecular Basis of Pediatric Autoimmune Diseases
  134. Immunopathogenesis of Celiac Disease
  135. Role of Tumor Microenvironment in Angiogenesis
  136. Pathogenesis of Viral Encephalitis
  137. Pathological Features of Gastroesophageal Reflux Disease (GERD)
  138. Molecular Mechanisms of Antiviral Drug Resistance
  139. Diagnostic Challenges in Pediatric Liver Pathology
  140. Immunohistochemical Profiling in Soft Tissue Sarcomas
  141. Pathophysiology of Hypertrophic Cardiomyopathy
  142. Genetic Variants in Amyotrophic Lateral Sclerosis (ALS)
  143. Pathological Changes in Autoimmune Thrombocytopenia
  144. Molecular Markers for Predicting Response to Targeted Immunotherapies
  145. Histopathological Characterization of Lymphatic System Disorders
  146. Diagnostic Challenges in Pediatric Rheumatologic Pathology
  147. Pathological Features of Autoimmune Gastritis
  148. Immunopathogenesis of Atopic Dermatitis
  149. Role of Tumor Microenvironment in Tumor Dormancy
  150. Pathogenesis of Viral Respiratory Infections
  151. Pathological Changes in Autoimmune Myasthenia Gravis
  152. Molecular Basis of Pediatric Neurological Disorders
  153. Immunohistochemical Profiling in Soft Tissue Tumors
  154. Pathophysiology of Aplastic Anemia
  155. Genetic Basis of Cystic Fibrosis
  156. Pathological Features of Autoimmune Hemorrhagic Disorders
  157. Molecular Mechanisms of Antifungal Drug Resistance
  158. Diagnostic Challenges in Pediatric Endocrine Pathology
  159. Immunopathogenesis of Eosinophilic Gastrointestinal Disorders
  160. Role of Tumor Microenvironment in Cancer Metastasis