Antibacteria Activity Of Bitter Orange (Citrus Aurantium) On Staphylococcus Aureus And Escherichia Coli Isolated From Wound Infection

Aim

The primary aim of this study is to investigate the antibacterial activity of bitter orange scientifically knowns as (Citrus aurantium) extract against Staphylococcus aureus and Escherichia coli isolated from wound infections.

Objectives:

To determine the minimum inhibitory concentration (MIC) of bitter orange extract against the isolated bacterial strains.

To compare the antibacterial activity of bitter orange extract with standard antibiotics commonly used to treat wound infections.

To investigate the potential synergistic effects of bitter orange extract in combination with standard antibiotics against Staphylococcus aureus and Escherichia coli.

Chapter One

Introduction

1.1 Background to the Study

1.2 Discussions on Bitter Orange (Citrus Aurantium)

1.3 Discuss on Staphylococcus Aureus

1.4 Overview on Escherichia Coli

1.5 Aims & Objectives

1.5.1 Aim

1.5.2 Objectives

1.6 Scopes of the Study

1.7 Limitations of the Study

Chapter Two

Literature Review

2.1 Introduction to Wound Infections

2.1.2 Overview of Wound Infections: Types, Causes, and Clinical Significance

2.1.3 Epidemiology of Wound Infections: Prevalence, Risk Factors, and Impact on Healthcare

2.2 Bacterial Pathogens Associated With Wound Infections

2.3 Antimicrobial Properties of Bitter Orange (Citrus Aurantium):

2.3.1 Traditional Uses of Bitter Orange in Folk Medicine: Historical Perspectives and Cultural Significance

2.3.2 Phytochemical Composition of Bitter Orange: Essential Oils, Flavonoids, and Other Bioactive Compounds

2.3.3 In Vitro and in Vivo Studies Investigating the Antibacterial Activity of Bitter Orange Against Various Pathogens

2.4 Assessment of Cytotoxicity and Genotoxicity of Bitter Orange Extract in Vitro and in Vivo.

2.4.1 In Vitro Studies

2.4.2 In Vivo Studies

Chapter Three

Materials and Methods

3.1 Study Area

3.2 Materials

3.3 Sample Collection

3.4 Sample Processing

3.5 Data Analysis

Chapter Four

Data Analys and Interpretation

4.1 Introduction

4.2 Minimum Inhibitory Concentrations (MICS)

4.2 Zone of Inhibition Diameters

4.4 Biochemical Test Results

Chapter Five

Discussion, Conclusion and Recommendation

5.1 Discussion

5.1.1 Explanation of Result Findings and Comparison With Previous Findings

5.1.2 Discussion Based on Specific Objectives

5.2 Conclusion

5.3 Recommendation

References

• Comparative Study Of Antibacterial Activity Of Two Selected Medicated Soap And One Local Black Soap On Staphylococcus Aureus From Wound Infection
• Antibacterial Activity Of Leptadenia Hastata On Some Selected Bacteria
• Antibacterial Activity Of Sweet Orange (Citrus Sinensis) On Staphylococcus Aureus And Escherichia Coli Isolated From Wound Infections
• Antibacterial Activity Of Three Types Of Medicated Soaps On Staphylococcus Aureus From Wound Infections
• Antibacterial Activity Of Honey On Staphylococcus Aureusescherichia Coli And Streptococcus Pyogen Isolated From Wound

• Science Laboratory Technology / Microbiology Project Topics and Materials